Gene name:
ERCC5 (ERCM2;XPG;XPGC) ;
Protein name:
DNA repair protein complementing XP-G cells ;
Alternative:
Xeroderma pigmentosum group G-complementing protein ;DNA excision repair protein ERCC-5 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with PCNA.
Function:
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MGVQGLWKLL | ECSGRQVSPE | ALEGKILAVD | ISIWLNQALK | GVRDRHGNSI |
100:
ENPHLLTLFH | RLCKLLFFRI | RPIFVFDGDA | PLLKKQTLVK | RRQRKDLASS |
150:
DSRKTTEKLL | KTFLKRQAIK | TAFRSKRDEA | LPSLTQVRRE | NDLYVLPPLQ |
200:
EEEKHSSEEE | DEKEWQERMN | QKQALQEEFF | HNPQAIDIES | EDFSSLPPEV |
250:
KHEILTDMKE | FTKRRRTLFE | AMPEESDDFS | QYQLKGLLKK | NYLNQHIEHV |
300:
QKEMNQQHSG | HIRRQYEDEG | GFLKEVESRR | VVSEDTSHYI | LIKGIQAKTV |
350:
AEVDSESLPS | SSKMHGMSFD | VKSSPCEKLK | TEKEPDATPP | SPRTLLAMQA |
400:
ALLGSSSEEE | LESENRRQAR | GRNAPAAVDE | GSISPRTLSA | IKRALDDDED |
450:
VKVCAGDDVQ | TGGPGAEEMR | INSSTENSDE | GLKVRDGKGI | PFTATLASSS |
500:
VNSAEEHVAS | TNEGREPTDS | VPKEQMSLVH | VGTEAFPISD | ESMIKDRKDR |
550:
LPLESAVVRH | SDAPGLPNGR | ELTPASPTCT | NSVSKNETHA | EVLEQQNELC |
600:
PYESKFDSSL | LSSDDETKCK | PNSASEVIGP | VSLQETSSIV | SVPSEAVDNV |
650:
ENVVSFNAKE | HENFLETIQE | QQTTESAGQD | LISIPKAVEP | MEIDSEESES |
700:
DGSFIEVQSV | ISDEELQAEF | PETSKPPSEQ | GEEELVGTRE | GEAPAESESL |
750:
LRDNSERDDV | DGEPQEAEKD | AEDSLHEWQD | INLEELETLE | SNLLAQQNSL |
800:
KAQKQQQERI | AATVTGQMFL | ESQELLRLFG | IPYIQAPMEA | EAQCAILDLT |
850:
DQTSGTITDD | SDIWLFGARH | VYRNFFNKNK | FVEYYQYVDF | HNQLGLDRNK |
900:
LINLAYLLGS | DYTEGIPTVG | CVTAMEILNE | FPGHGLEPLL | KFSEWWHEAQ |
950:
KNPKIRPNPH | DTKVKKKLRT | LQLTPGFPNP | AVAEAYLKPV | VDDSKGSFLW |
1000:
GKPDLDKIRE | FCQRYFGWNR | TKTDESLFPV | LKQLDAQQTQ | LRIDSFFRLA |
1050:
QQEKEDAKRI | KSQRLNRAVT | CMLRKEKEAA | ASEIEAVSVA | MEKEFELLDK |
1100:
AKGKTQKRGI | TNTLEESSSL | KRKRLSDSKG | KNTCGGFLGE | TCLSESSDGS |
1150:
SSEDAESSSL | MNVQRRTAAK | EPKTSASDSQ | NSVKEAPVKN | GGATTSSSSD |
1186:
SDDDGGKEKM | VLVTARSVFG | KKRRKLRRAR | GRKRKT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human DNA repair protein complementing XP-G cells
ELISA Kit for Human DNA repair protein complementing XP-G cells
CLIA Kit for Human DNA repair protein complementing XP-G cells
CLIA Kit for Human DNA repair protein complementing XP-G cells
Polyclonal Antibody for Human DNA repair protein complementing XP-G cells
Polyclonal Antibody for Human DNA repair protein complementing XP-G cells
Monoclonal Antibody for Human DNA repair protein complementing XP-G cells
Monoclonal Antibody for Human DNA repair protein complementing XP-G cells
Protein for Human DNA repair protein complementing XP-G cells
Protein for Human DNA repair protein complementing XP-G cells
R&D Technical Data
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS ARG-1053 AND ARG-1080
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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